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Description: JX06, a potent, selective and covalent PDK inhibitor, inhibits PDK1, PDK2 and PDK3 with IC50 of 49 nM, 101 nM and 313 nM respectively. Target: Dehydrogenase, Apoptosis, PDK. Smiles: S=C(SSC(=S)N1CCOCC1)N1CCOCC1. References: Sun W , Xie Z , Liu Y , et al. JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification[J]. Cancer Research, 2015:4923-4936.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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