JNK Inhibitor IX

JNK inhibitor IX is a thienylnaphthamide compound that targets the ATP binding site of JNK2 and JNK3, disrupting activity with pIC50 values of 6.5 and 6.7, respectively. It demonstrates little activity against JNK1, p38alpha, and a panel of more than 30 other kinases (pIC50 < 5.0).Formal Name: N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-1-naphthalenecarboxamide. CAS Number: 312917-14-9. Synonyms: c-Jun N-terminal Kinase Inhibitor IX, TCS JNK 5a. Molecular Formula: C20H16N2OS. Formula Weight: 332.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS(pH 7.2) (1:2): 0.25 mg/ml. lambdamax: 218, 316 nm. SMILES: O=C(C1=CC=CC2=C1C=CC=C2)NC3=C(C#N)C4=C(S3)CCCC4. InChi Code: InChI=1S/C20H16N2OS/c21-12-17-15-9-3-4-11-18(15)24-20(17)22-19(23)16-10-5-7-13-6-1-2-8-14(13)16/h1-2,5-8,10H,3-4,9,11H2,(H,22,23). InChi Key: WQGDQGAFSDMBLA-UHFFFAOYSA-N.