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Description: JG-98 is an allosteric Hsp70 inhibitor, displays high active against the breast cancer cell lines MDA-MB-231 and MCF-7 (EC50s: 0.4/0.7 µM). Target: HSP, Apoptosis. Smiles: [Cl-].CCn1\c(=C\c2scc[n+]2Cc2ccccc2)s\c(=C2\Sc3cc(Cl)ccc3N2C)c1=O. References: Li X, et al. Analogs of the Allosteric Heat Shock Protein 70 (Hsp70) Inhibitor, MKT-077, as Anti-Cancer Agents. ACS Med Chem Lett. 2013 Nov 14,4(11).
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