IRE1alpha kinase-IN-1
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: IRE1alpha kinase-IN-1 is a highly selective IRE1alpha (ERN1) inhibitor, with an IC50... more
Product information "IRE1alpha kinase-IN-1"
Description: IRE1alpha kinase-IN-1 is a highly selective IRE1alpha (ERN1) inhibitor, with an IC50 of 77 nM, displaying 100-fold selectivity over the IRE1beta isoform. It inhibits ER stress-induced IRE1alpha oligomerization and autophosphorylation, as well as IRE1alpha RNase activity (IC50=80 nM). Target: IRE1. Smiles: CN1CCC(CNc2cc(Cl)nn3c(cnc23)-c2cc3nc(Nc4ccccc4)[nH]c3cc2F)CC1
| Supplier: | TargetMol |
| Supplier-Nr: | T9564 |
Properties
| MW: | 504.99 D |
| Formula: | C26H26ClFN8 |
Database Information
| CAS : | 2328097-41-0| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H332, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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