Iloperidone metabolite P88

Iloperidone metabolite P88 is an active metabolite of the atypical antipsychotic iloperidone (Cay-22957). It binds to the serotonin (5-HT) receptor subtypes 5-HT1B, 5-HT2A, and 5-HT2C (Kis = 5.1, 0.03, and 6.9 nM, respectively), alpha2b- and alpha2c-adrenergic (Kis = 6 and 1.3 nM, respectively), and dopamine D1, D2A, and D4 receptors (Kis = 9.5, 1.6, and 3.5 nM, respectively).Formal Name: 4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxy-alpha-methyl-benzenemethanol. CAS Number: 133454-55-4. Synonyms: P88-8991. Molecular Formula: C24H29FN2O4. Formula Weight: 428.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: slightly soluble, Methanol: slightly soluble. SMILES: OC(C)C1=CC=C(OCCCN2CCC(C3=NOC4=C3C=CC(F)=C4)CC2)C(OC)=C1. InChi Code: InChI=1S/C24H29FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-17,28H,3,8-13H2,1-2H3. InChi Key: SBKZGLWZGZQVHA-UHFFFAOYSA-N.