Idelalisib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit... more
Product information "Idelalisib"
Description: Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110delta (IC50: 2.5 nM). The selectivity for p110delta is 40- to 300-fold than p110alpha/beta/gamma. Target: Autophagy, PI3K. Smiles: [C@H](NC1=C2C(N=CN2)=NC=N1)(CC)C=3N(C(=O)C=4C(N3)=CC=CC4F)C5=CC=CC=C5. References: Lannutti BJ, et al. CAL-101, a p110delta selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability. Blood. 2011 Jan 13,117(2):591-4.
| Keywords: | CAL-101, GS-1101 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1894 |
Properties
| Application: | Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta |
| MW: | 415.42 D |
| Formula: | C22H18FN7O |
Database Information
| CAS : | 870281-82-6| Matching products |
| KEGG ID : | K00922 | Matching products |
| Protein Atlas Nr. : | Lipid / Phosphoinositial Signaling |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H372 |
| P Phrases: | P260, P264, P270, P314, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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