ICI 89406
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A ß1-adrenergic receptor antagonist (IC50 = 4.2 nM), selective for ß1-adrenergic receptors over... more
Product information "ICI 89406"
A ß1-adrenergic receptor antagonist (IC50 = 4.2 nM), selective for ß1-adrenergic receptors over ß2-adrenergic receptors (IC50 = 678 nM), acts as a partial agonist at ß1- and ß2-adrenergic receptors, inducing cAMP accumulation in CHO-K1 cells expressing the human receptors (EC50s = 0.81 and 60.26 nM, respectively). Formulation: A solid. InChI: InChI=1S/C19H22N4O3/c20-12-15-6-4-5-9-18(15)26-14-17(24)13-21-10-11-22-19(25)23-16-7-2-1-3-8-16/h1-9,17,21,24H,10-11,13-14H2,(H2,22,23,25). InChIKey: HTLWRKRZKFAAAH-UHFFFAOYSA-N. SMILES: N#CC(C=CC=C1)=C1OCC(O)CNCCNC(NC2=CC=CC=C2)=O
| Keywords: | N-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-N'-phenyl-urea |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 42370 |
Properties
| Application: | SS1-adrenergic receptor antagonist |
| Immunogen: | 354.4 |
| MW: | 354.4 D |
| Formula: | C19H22N4O3 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 53671-71-9| Matching products |
| KEGG ID : | K04141 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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