Honokiol

Honokiol is a natural product derived from parts of the plant M. grandiflora used in Oriental herbal medicine. It is a lignan that produces diverse therapeutic effects, including acting as an anxiolytic in mice. Honokiol also inhibits nuclear factor-kappaB and phosphoinositide 3-kinase/Akt signaling, preventing inflammation, and interferes with angiogenesis while preventing tumor growth in vivo. It also scavenges superoxide and peroxyl radicals.Formal Name: 3',5-di-2-propen-1-yl-[1,1'-biphenyl]-2,4'-diol. CAS Number: 35354-74-6. Synonyms: NSC 293100. Molecular Formula: C18H18O2. Formula Weight: 266.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 33 mg/ml, DMSO: 33 mg/ml, Ethanol: 33 mg/ml, Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml. lambdamax: 258, 294 nm. SMILES: OC1=CC=C(CC=C)C=C1C2=CC(CC=C)=C(O)C=C2. InChi Code: InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2. InChi Key: FVYXIJYOAGAUQK-UHFFFAOYSA-N.