Description: Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2. Target: MEK, Akt, Autophagy, HCV Protease, ERK. Smiles: OC=1C(=CC(CC=C)=CC1)C2=CC(CC=C)=C(O)C=C2. References: Bai X, et al. J Biol Chem, 2003, 278(37),...

A phenolic compound isolated from Magnolia officinalis. It has many interesting biological activities. It inhibits leukotriene synthesis, protects rat heart mitochondria and liver from peroxidative injury, has anxiolytic and antiarrhythmic effects. It also possesses antimicrobial and antifungal activity. It was...

Honokiol is a natural product derived from parts of the plant M. grandiflora used in Oriental herbal medicine. It is a lignan that produces diverse therapeutic effects, including acting as an anxiolytic in mice. Honokiol also inhibits nuclear factor-kappaB and phosphoinositide 3-kinase/Akt signaling, preventing...

Light brown powder. Soluble in DMSO (30mg/ml), DMF (30mg/ml) or ethanol (30mg/ml). Chemical. CAS: 35354-74-6. Formula: C18H18O2. MW: 266.33. Honokiol is a natural product derived from parts of the plant M. grandiflora used in Oriental herbal medicine. It is a lignan with diverse biological activities, including...