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Halopemide is a potent inhibitor of phospholipase D (PLD), inhibiting human PLD1 and PLD2 in vitro (IC50 = 220 and 310 nM, respectively) and PLD activity in cells. Previously, halopemide has been found to inhibit dopamine receptors and was evaluated as a neuroleptic agent. Formal Name: N-[2-[4-(5-chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-ethyl]-4-fluoro-benzamide. CAS Number: 59831-65-1. Synonyms: NSC 354856, R34301. Molecular Formula: C21H22ClFN4O2. Formula Weight: 416.9. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 20 mg/ml, DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml, DMSO: 10 mg/ml. lambdamax: 293 nm. SMILES: ClC1=CC2=C(N(C3CCN(CCNC(C4=CC=C(F)C=C4)=O)CC3)C(N2)=O)C=C1. InChi Code: InChI=1S/C21H22ClFN4O2/c22-15-3-6-19-18(13-15)25-21(29)27(19)17-7-10-26(11-8-17)12-9-24-20(28)14-1-4-16(23)5-2-14/h1-6,13,17H,7-12H2,(H,24,28)(H,25,29). InChi Key: NBHPRWLFLUBAIE-UHFFFAOYSA-N.