GW6471
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: GW6471 is an antagonist of PPARalpha with IC50 of 0.24 µ M. GW6471 enhances the... more
Product information "GW6471"
Description: GW6471 is an antagonist of PPARalpha with IC50 of 0.24 µ M. GW6471 enhances the binding affinity of the PPAR alpha ligand-binding domain to the co-repressor proteins SMRT and NCoR. Target: PPAR. Smiles: CCC(=O)NC[C@H](Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)cc1)N\C(C)=C/C(=O)c1ccc(cc1)C(F)(F)F. References: Abu Aboud O, et al. Inhibition of PPARalpha induces cell cycle arrest and apoptosis, and synergizes with glycolysis inhibition in kidney cancer cells. PLoS One. 2013 Aug 7,8(8):e71115.
| Keywords: | GW 6471 |
| Supplier: | TargetMol |
| Supplier-Nr: | T8486 |
Properties
| Application: | PPARalpha antagonist |
| MW: | 619.67 D |
| Formula: | C35H36F3N3O4 |
Database Information
| CAS : | 880635-03-0| Matching products |
| KEGG ID : | K07294 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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