GP-AMC (hydrobromide)

GP-AMC is a fluorogenic substrate for dipeptidyl peptidase 4 (DPP-4). Upon enzymatic cleavage by DPP-4, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify DPP-4 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.Formal Name: glycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-prolinamide, monohydrobromide. CAS Number: 115035-46-6. Synonyms: Gly-Pro-AMC, Gly-Pro-7-amido-4-methylcoumarin. Molecular Formula: C17H19N3O4 . HBr. Formula Weight: 410.3. Purity: >98%. Emission: 440-460 nm. Excitation: 340-360 nm. Formulation: (Request formulation change), A solid. Solubility: DMF: 10 mg/ml, DMSO: 1 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 328 nm. SMILES: CC(C1=CC=C(NC([C@H]2N(C(CN)=O)CCC2)=O)C=C1O3)=CC3=O.Br. InChi Code: InChI=1S/C17H19N3O4.BrH/c1-10-7-16(22)24-14-8-11(4-5-12(10)14)19-17(23)13-3-2-6-20(13)15(21)9-18,/h4-5,7-8,13H,2-3,6,9,18H2,1H3,(H,19,23),1H/t13-,/m0./s1. InChi Key: PASXTQMFJRHMLJ-ZOWNYOTGSA-N.