Go697612-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo[2,3-a]pyrrollo[3,4-c]carbazol

Novel, very potent PKC inhibitor with high selectivity for the A-group of PKC isotypes (a, b and gamma), with IC50 values in the 2-10nM range. Little or no inhibition of the B- and C-groups of PKC isotypes, even at much higher concentrations. Solubility: Soluble in DMSO. , Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.