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Gö 6976
Item number: Cay13310-500
Gö 6976 is a nonglycosidic indolocarbazole that inhibits protein kinase C (PKC) with IC50 values of 2.3 and 6.2 nM for PKCalpha and PKCbeta1, respectively. It does not inhibit the activity of PKCdelta, PKCepsilon, or PKCzeta (IC50s > 3 µM), indicating a preference for the Ca2+-dependent subtypes, PKCalpha and...
| Keywords: | PD 406976, 5,6,7,13-tetrahydro-13-methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile |
| Application: | PKCalpha / PKCbeta1 inhibitor |
| CAS | 136194-77-9 |
| MW: | 378.4 D |
From 73.00€
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![Go697612-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo[2,3-a]pyrrollo[3,4-c]carbazol](https://www.biomol.com/media/image/cc/92/52/G8569-01-1_200x200.jpg "Go697612-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo[2,3-a]pyrrollo[3,4-c]carbazol")
Go697612-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-...
Item number: G8569-01.1
Novel, very potent PKC inhibitor with high selectivity for the A-group of PKC isotypes (a, b and gamma), with IC50 values in the 2-10nM range. Little or no inhibition of the B- and C-groups of PKC isotypes, even at much higher concentrations. Solubility: Soluble in DMSO. , Storage and Stability: May be stored at...
| CAS | 136194-77-9 |
| MW: | 378.43 |
338.00€
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Go6976
Item number: TGM-T6515-100mg
Description: Go6976 is a small molecule inhibitor of protein kinase C (PKC). Go6976 has been widely used in biomedical research as a tool to study the role of PKC in various physiological and pathophysiological processes. Target: PKC. Smiles: Cn1c2ccccc2c2c3C(=O)NCc3c3c4ccccc4n(CCC#N)c3c12. References: Hayamitsu...
| Keywords: | Gö 6976 |
| Application: | PKCalpha / PKCbeta1 inhibitor |
| CAS | 136194-77-9 |
| MW: | 378.43 D |
From 65.00€
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