GNF4877
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You can also order by e-mail: info@biomol.com
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: GNF4877 is a potent inhibitor of DYRK1A and GSK3beta (IC50s: 6 nM and 16 nM,... more
Product information "GNF4877"
Description: GNF4877 is a potent inhibitor of DYRK1A and GSK3beta (IC50s: 6 nM and 16 nM, respectively), resulting in the blockade of nuclear export of nuclear factor of activated T-cells (NFATc) and increased beta-cell proliferation. Target: DYRK, GSK-3. Smiles: CC(C)Oc1ccc(F)c(c1)-c1cnc(N)c(n1)C(=O)Nc1cnccc1N1CCC[C@H](C1)C(O)=O. References: Shen W, et al. Inhibition of DYRK1A and GSK3beta induces human beta-cell proliferation. Nat Commun. 2015 Oct 26,6:8372.
| Supplier: | TargetMol |
| Supplier-Nr: | T11447 |
Properties
| MW: | 494.52 D |
| Formula: | C25H27FN6O4 |
Database Information
| CAS : | 2041073-22-5| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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