2 products were found matching "2041073-22-5"!
No results were found for the filter!
GNF-4877
Item number: Cay42538-1
A Dyrk1a and Gsk3ß inhibitor (IC50s = 6 and 16 nM, respectively, for the mouse enzymes), selective for Dyrk1a and Gsk3ß over a panel of 57 kinases but does inhibit 10 other kinases at 1 µM, increases the proliferation of R7T1 mouse pancreatic ß-cells and primary human pancreatic ß-cells (EC50s = 0.66 and 0.54 µM,...
| Keywords: | (3R)-1-[3-[[[3-amino-6-[2-fluoro-5-(1-methylethoxy)phenyl]-2-pyrazinyl]carbonyl]amino]-4-pyridinyl]-3-piperidinecarboxylic... |
| Application: | Dyrk1a / Gsk3beta inhibitor |
| CAS | 2041073-22-5 |
| MW: | 494.52 D |
From 44.00€
*
GNF4877
Item number: TGM-T11447-10mg
Description: GNF4877 is a potent inhibitor of DYRK1A and GSK3beta (IC50s: 6 nM and 16 nM, respectively), resulting in the blockade of nuclear export of nuclear factor of activated T-cells (NFATc) and increased beta-cell proliferation. Target: DYRK, GSK-3. Smiles:...
| CAS | 2041073-22-5 |
| MW: | 494.52 D |
From 120.00€
*
