GNE-8505

Item number	Size	Manual	Delivery time	Price
Cay44006-1	1 mg	-	6 - 10 business days*	115.00€
Cay44006-5	5 mg	-	6 - 10 business days*	454.00€
Cay44006-10	10 mg	-	6 - 10 business days*	680.00€

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GNE-8505 is an inhibitor of dual leucine zipper kinase (DLK). It decreases the levels of... more

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Product information "GNE-8505"

GNE-8505 is an inhibitor of dual leucine zipper kinase (DLK). It decreases the levels of phosphorylated JNK in retinal lysates prepared from a mouse model of optic nerve crush when administered at doses of 3, 7, or 18 mg/kg. InChI: InChI=1S/C21H24F3N5O/c22-21(23,24)16-3-12(5-26-20(16)25)17-4-18(29(27-17)6-11-1-2-11)19-14-7-28(8-15(14)19)13-9-30-10-13/h3-5,11,13-15,19H,1-2,6-10H2,(H2,25,26)/t14-,15+,19+ InChIKey: IRPVABHDSJVBNZ-QWHZDKJVSA-N SMILES: NC1=NC=C(C2=NN(CC3CC3)C([C@H]4[C@@]5(CN(C[C@@]54[H])C6COC6)[H])=C2)C=C1C(F)(F)F

Keywords:	5-[1-(cyclopropylmethyl)-5-[(1alpha,5alpha,6alpha)-3-(3-oxetanyl)-3-azabicyclo[3.1.0]hex-6-yl]-1H-pyrazol-3-yl]-3-(trifluoromethyl)-2-pyridinamine
Supplier:	Cayman Chemical
Supplier-Nr:	44006

Properties

Application:	Dual leucine zipper bearing kinase (DLK) inhibitor
MW:	419.4 D
Formula:	C21H24F3N5O
Purity:	>98%
Format:	Solid

Database Information

CAS :	1620573-48-9\| Matching products
KEGG ID :	K04423 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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