Gefapixant
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at... more
Product information "Gefapixant"
Description: Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Target: P2X Receptor. Smiles: COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1S(N)(=O)=O. References: Ford AP, In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization. Purinergic Signal. 2012 Feb,8(Suppl 1):3-26.
| Keywords: | RO 4926219 , AF219 , MK-7264 |
| Supplier: | TargetMol |
| Supplier-Nr: | T5099 |
Properties
| Application: | Targets P2X purinoceptor 3 (P2RX3) |
| MW: | 353.4 D |
| Formula: | C14H19N5O4S |
Database Information
| CAS : | 1015787-98-0| Matching products |
| KEGG ID : | K05217 | Matching products |
| Protein Atlas Nr. : | Neuropharmacologics/Ion Channel Modulators |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H410 |
| P Phrases: | P264, P270, P273, P330, P391, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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