Gallamine (iodide)

Gallamine is an allosteric modulator of muscarinic acetylcholine receptors. It slows the dissociation of the muscarinic antagonist [3H]NMS from M1-M5 muscarinic receptors, with the highest potency for M2 receptors. Gallamine is cardioselective, inhibiting [3H]NMS binding in rat heart tissue homogenates more potently than in other tissues (IC50s = 0.8 and 3-30 µM, respectively). Formulations containing gallamine have previously been used as neuromuscular blockers during surgery.Formal Name: 2,2',2''-[1,2,3-benzenetriyltris(oxy)]tris[N,N,N-triethyl]-ethanaminium, triiodide. CAS Number: 65-29-2. Molecular Formula: C30H60N3O3 . 3I. Formula Weight: 891.5. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Slightly Soluble, Methanol: Slightly Soluble, Water: Slightly Soluble. SMILES: CC[N+](CC)(CC)CCOC1=C(OCC[N+](CC)(CC)CC)C(OCC[N+](CC)(CC)CC)=CC=C1.[I-].[I-].[I-]. InChi Code: InChI=1S/C30H60N3O3.3HI/c1-10-31(11-2,12-3)22-25-34-28-20-19-21-29(35-26-23-32(13-4,14-5)15-6)30(28)36-27-24-33(16-7,17-8)18-9,,,/h19-21H,10-18,22-27H2,1-9H3,3*1H/q+3,,,/p-3. InChi Key: REEUVFCVXKWOFE-UHFFFAOYSA-K.