Farnesyl Thiosalicylic Acid Amide

Farnesyl Thiosalicylic Acid Amide
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay13175-1 1 mg -

6 - 10 business days*

Cay13175-5 5 mg -

6 - 10 business days*

Cay13175-10 10 mg -

6 - 10 business days*

Cay13175-50 50 mg -

6 - 10 business days*

Association of Ras protein with the inner surface of the plasma membrane is required for Ras... more
Product information "Farnesyl Thiosalicylic Acid Amide"
Association of Ras protein with the inner surface of the plasma membrane is required for Ras signaling activity. Farnesyl thiosalicylic acid (FTS) amide is an FTS derivative with an amide added to the carboxyl group. FTS amide inhibits the growth of PANC-1 and U87 tumor cells with IC50 values of 20 and 10 µM, respectively, a relatively higher potency compared to that of FTS (IC50s = 35 and 50 µM, respectively). Treatment of nude mice bearing either U87 glioblastoma or PANC-1 tumors with 100 mg/kg FTS amide twice daily for four days inhibits tumor growth by at least 50% of controls. Formal Name: 2-[[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]thio]-benzamide. CAS Number: 1092521-74-8. Synonyms: FTS Amide, Salirasib Amide. Molecular Formula: C22H31NOS. Formula Weight: 357.6. Purity: >96%. Formulation: A solution in ethanol. Solubility: DMF: 12 mg/ml, DMSO: 10 mg/ml, Ethanol: 20 mg/ml. SMILES: C\C(CC/C=C(CC/C=C(C)\C)\C)=C/CSC1=C(C(N)=O)C=CC=C1. InChi Code: InChI=1S/C22H31NOS/c1-17(2)9-7-10-18(3)11-8-12-19(4)15-16-25-21-14-6-5-13-20(21)22(23)24/h5-6,9,11,13-15H,7-8,10,12,16H2,1-4H3,(H2,23,24)/b18-11+,19-15+. InChi Key: GZTMFRUGZMZCRD-CFBAGHHKSA-N.
Keywords: FTS Amide, Salirasib Amide, 2-[[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]thio]-benzamide
Supplier: Cayman Chemical
Supplier-Nr: 13175


Application: Ras signaling inhibitor
MW: 357.6 D
Formula: C22H31NOS
Purity: >96%
Format: Solution

Database Information

CAS : 1092521-74-8| Find alternatives
KEGG ID : K02833 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Our products are for laboratory research use only: Not for administration to humans!
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