Etravirine
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase... more
Product information "Etravirine"
Description: Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that confer resistance to the two most commonly prescribed first-generation NNRTIs. It can bind the enzyme reverse transcriptase (RT) in multiple conformations, both for native and mutant RT, thereby blocking the enzymatic activity of RT. Target: HIV Protease, Reverse Transcriptase. Smiles: O(C1=NC(NC2=CC=C(C#N)C=C2)=NC(N)=C1Br)C3=C(C)C=C(C#N)C=C3C. References: Das K, et al. J Med Chem, 2004, 47(10), 2550-2560.
| Keywords: | TMC125, R165335 |
| Supplier: | TargetMol |
| Supplier-Nr: | T2551 |
Properties
| Application: | Targets HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13] (RT) |
| MW: | 435.28 D |
| Formula: | C20H15BrN6O |
Database Information
| CAS : | 269055-15-4| Matching products |
| KEGG ID : | K24802 | Matching products |
| Protein Atlas Nr. : | Microbiology |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H413 |
| P Phrases: | P264, P270, P273, P330, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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