39 products were found matching "K24802"!
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Lodenosine
Item number: TGM-T19688-100mg
Description: Lodenosine is an inhibitor of RNA-directed DNA polymerase, and potentially for the treatment of HIV. Target: Others. Smiles: F[C@@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CO)C1. References: Bei N, Li G, Meng Z, Weng Y, Zavala M, Molina LT. Impacts of using an ensemble Kalman filter on air quality...
| Keywords: | FddA, 3'-dideoxyarabinosyladenine, Fddl, DDG-1, 2'-Fluoro-2', 2'-F-dd-ara-A |
| Application: | Targets HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13] (RT) |
| CAS | 110143-10-7 |
| MW: | 253.23 D |
From 1,520.00€
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Raluridine
Item number: TGM-T19689-100mg
Description: Raluridine is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection. 935U83 inhibited virus growth with an average 50% inhibitory concentration (IC50: 1.8 microM) corresponding IC50s were 0.10 microM for FLT (3'-deoxy-3'-fluorothymidine) and 0.23, 0.49, and 0.03 microM...
| Keywords: | BW-935U-83, DRG-0215, 935U-83, FddClUrd, FCU |
| Application: | Targets HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13] (RT) |
| CAS | 119644-22-3 |
| MW: | 264.64 D |
From 1,971.00€
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Ulonivirine
Item number: TGM-T63308-100mg
Description: Ulonivirine is an orally active non-nucleoside reverse transcriptase inhibitor that exhibits high antiviral activity and can be used to study HIV-1 infection. Target: Others. Smiles: O(C1=C(C(F)(F)F)N=CN(CC=2C=C(C(F)(F)F)C(=O)NN2)C1=O)C3=CC(C#N)=CC(Cl)=C3
| Application: | Targets HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13] (RT) |
| CAS | 1591823-76-5 |
| MW: | 491.73 D |
From 234.00€
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Abacavir sulfate
Item number: TGM-T6367-100mg
Description: Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity. Target: Reverse Transcriptase, Apoptosis, HIV Protease. Smiles: O=S(O)(O)=O.OC[C@H](C=C1)C[C@H]1N2C3=NC(N)=NC(NC4CC4)=C3N=C2.OC[C@H](C=C5)C[C@H]5N6C7=NC(N)=NC(NC8CC8)=C7N=C6. References: Mallal S, et al....
| Keywords: | Abacavir Hemisulfate, 1592U89, ABC sulfate, Ziagen |
| Application: | Targets HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13] (RT) |
| CAS | 188062-50-2 |
| MW: | 335.38 D |
From 40.00€
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Stavudine
Item number: TGM-T1404-100mg
Description: Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV. Target: Apoptosis, HIV Protease, NOD-like Receptor (NLR), Autophagy, Reverse Transcriptase, Nucleoside Antimetabolite/Analog. Smiles: CC1=CN(C2OC(CO)C=C2)C(=O)NC1=O. References: Caron...
| Keywords: | d4T, Sanilvudine, BMY-27857, NSC 163661 |
| Application: | Targets HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13] (RT) |
| CAS | 3056-17-5 |
| MW: | 224.21 D |
From 34.00€
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Abacavir
Item number: TGM-T1267-100mg
Description: Abacavir (Ziagen) is a nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to the immune system, and reduces the risk of developing AIDS. Target: Reverse Transcriptase, HIV Protease, Apoptosis. Smiles:...
| Keywords: | Abacavir sulfate, Ziagen, Epzicom |
| Application: | Targets HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13] (RT) |
| CAS | 136470-78-5 |
| MW: | 286.33 D |
From 31.00€
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Loviride
Item number: TGM-T15776-1mL
Description: Loviride is a non-nucleoside reverse transcriptase inhibitor (IC50: 0.3 µM). Loviride inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells. It is used for reverse transcriptase from HIV-1. Target: Others. Smiles: CC(=O)c1ccc(C)cc1NC(C(N)=O)c1c(Cl)cccc1Cl. References: Witvrouw M, et al. Activity of...
| Keywords: | R 89439 |
| Application: | Targets HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13] (RT) |
| CAS | 147362-57-0 |
| MW: | 351.23 D |
162.00€
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Zidovudine
Item number: TGM-T1416-100mg
Description: Zidovudine (ZDV) is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines. Target: CRISPR/Cas9, HIV...
| Keywords: | AZT, NSC 602670, Azidothymidine, ZDV |
| Application: | Targets HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13] (RT) |
| CAS | 30516-87-1 |
| MW: | 267.24 D |
From 45.00€
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Azvudine
Item number: TGM-T14489-100mg
Description: Azvudine (FNC) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine inhibits NRTI-resistant viral strains. Azvudine exerts highly potent inhibition on HIV-1 (EC50s ranging from 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025...
| Keywords: | RO-0622, FNC |
| Application: | NRTI (nucleoside reverse transcriptase inhibitor ) |
| CAS | 1011529-10-4 |
| MW: | 286.22 D |
From 57.00€
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Nevirapine
Item number: TGM-T1595-100mg
Description: Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preventing the damage to the immune system and reducing the risk of developing AIDS....
| Keywords: | NSC 641530, BI-RG 587, NVP |
| Application: | Targets HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13] (RT) |
| CAS | 129618-40-2 |
| MW: | 266.3 D |
From 31.00€
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Islatravir
Item number: TGM-T16098-100mg
Description: Islatravir (MK-8591) is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively). Target: Reverse Transcriptase, HIV Protease. Smiles:...
| Keywords: | MK-8591 |
| Application: | Targets HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13] (RT) |
| CAS | 865363-93-5 |
| MW: | 293.25 D |
From 72.00€
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Rovafovir Etalafenamide
Item number: TGM-T24731-100mg
Description: Rovafovir Etalafenamide is a prodrug of anti-HIV nucleoside phosphonate. Target: Others. Smiles: FC=1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](OCP(OC4=CC=CC=C4)(N[C@H](C(OCC)=O)C)=O)C1. References: Rai MA, Pannek S, Fichtenbaum CJ. Emerging reverse transcriptase inhibitors for HIV-1 infection. Expert Opin...
| Keywords: | GS9131, GS 9131, GS-9131 |
| Application: | Targets HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13] (RT) |
| CAS | 912809-27-9 |
| MW: | 506.42 D |
From 2,272.00€
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