Ethyl-L-NIO (hydrochloride)

Ethyl-L-NIO (hydrochloride)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10012088-5 5 mg -

6 - 10 business days*

54.00€
Cay10012088-10 10 mg -

6 - 10 business days*

103.00€
Cay10012088-50 50 mg -

6 - 10 business days*

430.00€
Cay10012088-100 100 mg -

6 - 10 business days*

753.00€
 
Ethyl-L-NIO, the saturated analog of vinyl-L-NIO, is a modestly selective NOS inhibitor. The Ki... more
Product information "Ethyl-L-NIO (hydrochloride)"
Ethyl-L-NIO, the saturated analog of vinyl-L-NIO, is a modestly selective NOS inhibitor. The Ki values for inhibition of nNOS, eNOS, and iNOS by ethyl-L-NIO are 5.3, 18, and 12 µM, respectively, as determined using initial rate measurements. However when evaluating the Ki/Km ratio, ethyl-L-NIO does not show biologically significant selectivity for nNOS over eNOS, and instead favors iNOS (Ki/Km = 3.79, 5, and 0.96 µM, respectively). Although ethyl-L-NIO inhibits nNOS, it does not inactivate nNOS in the presence of NADPH and O2. Formal Name: N5-(1-iminobutyl)-L-ornithine, monohydrochloride. CAS Number: 150403-97-7. Synonyms: L-N5-(1-Iminobutyl)ornithine hydrochloride. Molecular Formula: C9H19N3O2 . HCl. Formula Weight: 237.7. Purity: >95%. Formulation: A crystalline solid. Solubility: DMF: 0.3 mg/ml, DMSO: 2 mg/ml, Ethanol: 2.5 mg/ml, PBS (pH 7.2): 5 mg/ml. SMILES: CCCC(=N)NCCC[C@H](N)C(=O)OCl. InChi Code: InChI=1S/C9H19N3O2.ClH/c1-2-4-8(11)12-6-3-5-7(10)9(13)14,/h7H,2-6,10H2,1H3,(H2,11,12)(H,13,14),1H. InChi Key: DWNWLIPSWIUXRG-UHFFFAOYSA-N.
Keywords: L-N5-(1-Iminobutyl)ornithine hydrochloride, N5-(1-iminobutyl)-L-ornithine, monohydrochloride
Supplier: Cayman Chemical
Supplier-Nr: 10012088

Properties

Application: NOS inhibitor
MW: 237.7 D
Formula: C9H19N3O2 . HCl
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 150403-97-7| Find alternatives
KEGG ID : K13240 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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