(-)-Epicatechin

(-)-Epicatechin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay11807-1 1 mg -

6 - 10 business days*

44.00€
Cay11807-5 5 mg -

6 - 10 business days*

149.00€
Cay11807-10 10 mg -

6 - 10 business days*

231.00€
Cay11807-25 25 mg -

6 - 10 business days*

469.00€
 
(-)-Epicatechin is a polyketide synthase-derived polyphenol flavonoid that has been found in T.... more
Product information "(-)-Epicatechin"
(-)-Epicatechin is a polyketide synthase-derived polyphenol flavonoid that has been found in T. cacao and has diverse biological activities. It scavenges DPPH (Cay-14805) radicals in a cell-free assay when used at a concentration of 5 µM. (-)-Epicatechin inhibits COX-1 (IC50 = 3.2 µM). It acts synergistically with epigallocatechin gallate (Cay-70935) to induce apoptosis in, and reduce the proliferation of, PC-9 lung cancer cells when used at a concentration of 200 µM. (-)-Epicatechin (80 mg/kg) reduces LPS-induced increases in plasma creatinine and urea levels in a rat model of renal inflammation.Formal Name: 2R-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3R,5,7-triol. CAS Number: 490-46-0. Synonyms: epi-Catechin, NSC 81161. Molecular Formula: C15H14O6. Formula Weight: 290.3. Purity: >90%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 12.5 mg/ml, DMSO: 12.5 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 278 nm. SMILES: OC1=CC2=C(C[C@@H](O)[C@@H](C3=CC=C(O)C(O)=C3)O2)C(O)=C1. InChi Code: InChI=1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15-/m1/s1. InChi Key: PFTAWBLQPZVEMU-UKRRQHHQSA-N. Origin: Plant/Acacia catechu.
Keywords: epi-Catechin, NSC 81161, 2R-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3R,5,7-triol
Supplier: Cayman Chemical
Supplier-Nr: 11807

Properties

Application: Antioxidant, apoptosis inducer
MW: 290.3 D
Formula: C15H14O6
Purity: >90%
Format: Crystalline Solid

Database Information

CAS : 490-46-0| Matching products
KEGG ID : K00509 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335, H401
P Phrases: P261, P264, P271, P273, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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