(E)-4-hydroxy Tamoxifen

(E)-4-hydroxy Tamoxifen is an active metabolite of tamoxifen (Cay-13258, Cay-11629) and (Z)-4-hydroxy tamoxifen (Cay-14854). It is formed from tamoxifen via transisomerization of the (Z)-4-hydroxy tamoxifen intermediate by the cytochrome P450 isoforms CYP1A1, CYP1B1, CYP2B6, CYP2D6, CYP3A4, and CYP3A5. (E)-4-hydroxy Tamoxifen inhibits estradiol benzoate-induced increases in oviduct weight in quails (ED50 = 2. mg/kg). Formal Name: 4-[(1E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol. CAS Number: 174592-47-3. Synonyms: (E)-Afimoxifene (E)-4-OHT cis-4-hydroxy Tamoxifen. Molecular Formula: C26H29NO2. Formula Weight: 387.5. Purity: >98%. Formulation (Request formulation change): A solid. Solubility: DMSO: Sparingly soluble: 1-10 mg/ml Ethanol: Slightly soluble: 0.1-1 mg/ml. SMILES: CC/C(C1=CC=CC=C1)=C(C2=CC=C(C=C2)O)\C3=CC=C(OCCN(C)C)C=C3. InChi Code: InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3/b26-25+. InChi Key: TXUZVZSFRXZGTL-OCEACIFDSA-N. Storage: -20°C. Stability: > 4 years.