Dopamine

Dopamine is an endogenous catecholamine neurotransmitter synthesized from the amino acid L-tyrosine that acts as an agonist at dopamine receptors (D1-5). Dopamine is mainly synthesized in the substantia nigra and ventral tegmental area and is a precursor in norepinephrine and epinephrine biosynthesis. Dopamine-containing neurons in the brain are involved in reward-motivated behavior, motor control, and hormone release. Dopamine is also synthesized in the adrenal glands where it exerts peripheral paracrine functions including control of vasodilation, sodium excretion, insulin production, gastrointestinal motility, and the activity of lymphocytes. Loss or damage of dopaminergic neurons in the substantia nigra is associated with Parkinson's disease.Formal Name: 4-(2-aminoethyl)-1,2-benzenediol. CAS Number: 51-61-6. Synonyms: DA, 3-hydroxy Tyramine, KW 3160, NSC 173182. Molecular Formula: C8H11NO2. Formula Weight: 153.2. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: insol, DMSO: 1 mg/ml, Ethanol: insol, PBS (pH 7.2): insol. SMILES: OC1=CC=C(CCN)C=C1O. InChi Code: InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2. InChi Key: VYFYYTLLBUKUHU-UHFFFAOYSA-N.