DDD85646

Item number	Size	Delivery time	Price
TGM-T27135-1mg	1 mg	7 - 10 business days*	97.00€
TGM-T27135-5mg	5 mg	7 - 10 business days*	315.00€
TGM-T27135-1mL	1 ml	7 - 10 business days*	345.00€
TGM-T27135-10mg	10 mg	7 - 10 business days*	491.00€
TGM-T27135-25mg	25 mg	7 - 10 business days*	717.00€
TGM-T27135-50mg	50 mg	7 - 10 business days*	996.00€
TGM-T27135-100mg	100 mg	7 - 10 business days*	1,370.00€

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Description: DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM,... more

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Product information "DDD85646"

Description: DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM. Target: Parasite. Smiles: Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1. References: Bayliss T, Robinson DA, Smith VC, Brand S, McElroy SP, Torrie LS, Mpamhanga C, Norval S, Stojanovski L, Brenk R, Frearson JA, Read KD, Gilbert IH, Wyatt PG. Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors. J Med Chem. 2017 Nov 10. doi: 10.1021/acs.jmedchem.7b01255. [Epub ahead of print] PubMed PMID: 29125744.

Keywords:	DDD 85646, DDD-85646
Supplier:	TargetMol
Supplier-Nr:	T27135

Properties

MW:	495.43 D
Formula:	C21H24Cl2N6O2S

Database Information

CAS :

1215010-55-1| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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