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DDD85646
Item number: Cay13839-1
DDD85646 is a moderately bioavailable pyrazole sulphonamide inhibitor of T. brucei N-myristoyltransferase (TbNMT) with an apparent Ki value of 1.44 nM. T. brucei is the parasite responsible for human African trypanosomiasis (HAT), also known as African sleeping sickness, and is transmitted through the tsetse fly....
| Keywords: | IMP-366, 2,6-dichloro-4-[2-(1-piperazinyl)-4-pyridinyl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)-benzenesulfonamide |
| Application: | Trypanosoma brucei N-myristoyltransferase (TbNMT) inhibitor |
| CAS | 1215010-55-1 |
| MW: | 495.4 D |
From 133.00€
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DDD85646
Item number: TGM-T27135-100mg
Description: DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM. Target: Parasite. Smiles: Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1. References: Bayliss T, Robinson DA, Smith VC, Brand S, McElroy SP,...
| Keywords: | DDD 85646, DDD-85646 |
| CAS | 1215010-55-1 |
| MW: | 495.43 D |
From 97.00€
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