DB2313

Item number	Size	Delivery time	Price
TGM-T9707-1mg	1 mg	7 - 10 business days*	49.00€
TGM-T9707-5mg	5 mg	7 - 10 business days*	120.00€
TGM-T9707-10mg	10 mg	7 - 10 business days*	195.00€
TGM-T9707-25mg	25 mg	7 - 10 business days*	453.00€
TGM-T9707-50mg	50 mg	7 - 10 business days*	671.00€

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Description: DB2313 (Carboximidamide) is a potent transcription factor PU.1 inhibitor, IC50=14... more

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Product information "DB2313"

Description: DB2313 (Carboximidamide) is a potent transcription factor PU.1 inhibitor, IC50=14 nM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis of acute myeloid leukemia (AML) cells, and has anticancer effects. Target: Apoptosis. Smiles: CC(C)NC(=N)c1ccc2nc([nH]c2c1)-c1ccc(OCc2cccc(COc3ccc(cc3)-c3nc4ccc(cc4[nH]3)C(=N)NC(C)C)c2F)cc1. References: Iléana Antony-Debré, et al. Pharmacological inhibition of the transcription factor PU.1 in leukemia. J Clin Invest. 2017 Dec 1,127(12):4297-4313.

Keywords:	Carboximidamide
Supplier:	TargetMol
Supplier-Nr:	T9707

Properties

Application:	PU.1 inhibitor
MW:	708.83 D
Formula:	C42H41FN8O2

Database Information

CAS :	2170606-74-1\| Matching products
KEGG ID :	K09438 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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