2 products were found matching "2170606-74-1"!

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Item number: TGM-T9707-5mg

Description: DB2313 (Carboximidamide) is a potent transcription factor PU.1 inhibitor, IC50=14 nM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis of acute myeloid leukemia (AML) cells, and has anticancer effects. Target: Apoptosis. Smiles:...

Keywords:	Carboximidamide
Application:	PU.1 inhibitor
CAS	2170606-74-1
MW:	708.83 D

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DB2313 (hydrochloride)

Item number: Cay35021-1

DB2313 is an inhibitor of the transcription factor PU.1 (IC50 = 14 nM). Long-term exposure of DB2313 (300 nM) to Kit+/Sca-1+/Lin- hematopoietic stem progenitor cells (KSL-HSPCs) reduces colony formation. DB2313 (700 nM) decreases ovalbumin-induced reprogramming of isolated mouse neutrophils into antigen-presenting...

Keywords:	2,2'-[(2-fluoro-1,3-phenylene)bis(methyleneoxy-4,1-phenylene)]bis[N-(1-methylethyl)-1H-benzimidazole-6-carboximidamide
Application:	PU.1 inhibitor
CAS	2170606-74-1
MW:	708.8 D

From 39.00€ *

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