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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| BPS-27013 | 10 mg | - | - |
3 - 15 business days* |
276.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Cyclopamine inhibits activation of the Hedgehog response pathway by binding to and inhibiting the... more
Product information "Cyclopamine, Free Base"
Cyclopamine inhibits activation of the Hedgehog response pathway by binding to and inhibiting the proto-oncogene Smoothened (SMO). The effects of oncogenic mutations that either activate SMO or inactivate the tumor suppressor Patched (Ptch) can be reversed by cyclopamine treatment. Cyclopamine has also been shown to induce apoptosis in colorectal adenoma cell lines, carcinoma-derived cell lines, and skin basal cell carcinomas and is being investigated as an anti-cancer drug.
| Supplier: | BPS Bioscience |
| Supplier-Nr: | 27013 |
Properties
| Application: | SMO inhibitor |
| MW: | 411.6 D |
| Formula: | C27H41NO2 |
Database Information
| KEGG ID : | K06226 | Matching products |
Handling & Safety
| Storage: | -20°C (Store aqueous sol. one day max) |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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