CUR61414
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: CUR61414 is a cell-permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200... more
Product information "CUR61414"
Description: CUR61414 is a cell-permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM) and selectively binds to smoothened (Ki = 44 nM). Target: Hedgehog/Smoothened. Smiles: COc1cccc(CN([C@H]2C[C@H](N(Cc3ccc4OCOc4c3)C2)C(=O)N2CCNCC2)C(=O)CC(C)(C)C)c1. References: Williams JA, et al. Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions.Proc Natl Acad Sci U S A. 2003 Apr 15,100(8):4616-21. Epub 2003 Apr 4.
| Supplier: | TargetMol |
| Supplier-Nr: | T15019 |
Properties
| Application: | Smoothened antagonist |
| MW: | 550.69 D |
| Formula: | C31H42N4O5 |
Database Information
| CAS : | 334998-36-6| Matching products |
| KEGG ID : | K06226 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301 |
| P Phrases: | P264, P270, P321, P330, P301+P310, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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