Crenigacestat

Item number	Size	Delivery time	Price
TGM-T3633-1mg	1 mg	7 - 10 business days*	57.00€
TGM-T3633-5mg	5 mg	7 - 10 business days*	120.00€
TGM-T3633-1mL	1 ml	7 - 10 business days*	122.00€
TGM-T3633-10mg	10 mg	7 - 10 business days*	198.00€
TGM-T3633-25mg	25 mg	7 - 10 business days*	371.00€
TGM-T3633-50mg	50 mg	7 - 10 business days*	-

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Description: Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of... more

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Product information "Crenigacestat"

Description: Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most tumor cell lines tested. It effectively inhibits mutant Notch receptor activity and, in a xenograft tumor model, inhibits the expression of Notch-regulated genes and N1ICD cleavage in the tumor microenvironment. Target: Gamma-secretase. Smiles: C[C@H](NC(=O)CCC(F)(F)F)C(=O)N[C@H]1c2ccccc2-c2cccnc2N(CCO)C1=O. References: Eli Lilly Company. The 8th SCI-RSC Symposium on Proteinase Inhibitor Design. 2013.

Keywords:	LY3039478
Supplier:	TargetMol
Supplier-Nr:	T3633

Properties

Application:	Targets Notch 1 (NOTCH1)
MW:	464.44 D
Formula:	C22H23F3N4O4

Database Information

CAS :	1421438-81-4\| Matching products
KEGG ID :	K02599 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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