CPCCOEt

CPCCOEt is a low affinity, selective, non-competitive antagonist of the metabotropic glutamate receptor subtype mGluR1b. It has been shown to inhibit glutamate-induced increases in intracellular calcium at human mGluR1b with an IC50 value of 6.5 µM while having no agonist or antagonist activity at mGluR2, -4a, -5a, -7b, and -8a at concentrations up to 100 µM.Formal Name: 7,7a-dihydro-7-(hydroxyimino)-benzo[b]cyclopropa[e]pyran-1a(1H)-carboxylic acid, ethyl ester. CAS Number: 179067-99-3. Molecular Formula: C13H13NO4. Formula Weight: 247.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 100 mM. SMILES: CCOC(C1(C2)C2/C(C3=CC=CC=C3O1)=N\O)=O. InChi Code: InChI=1S/C13H13NO4/c1-2-17-12(15)13-7-9(13)11(14-16)8-5-3-4-6-10(8)18-13/h3-6,9,16H,2,7H2,1H3/b14-11-. InChi Key: FXCTZFMSAHZQTR-KAMYIIQDSA-N.