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Item number: Cay21486-1

CPCCOEt is a low affinity, selective, non-competitive antagonist of the metabotropic glutamate receptor subtype mGluR1b. It has been shown to inhibit glutamate-induced increases in intracellular calcium at human mGluR1b with an IC50 value of 6.5 µM while having no agonist or antagonist activity at mGluR2, -4a, -5a,...

Keywords:	7,7a-dihydro-7-(hydroxyimino)-benzo[b]cyclopropa[e]pyran-1a(1H)-carboxylic acid, ethyl ester
Application:	Low affinity, selective, non-competitive mGluR1b antagonist
CAS	179067-99-3
MW:	247.3 D

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CPCCOEt

Item number: TGM-T22692-100mg

Description: CPCCOEt is a low-affinity, selective, non-competitive, and reversible antagonist of mGluR1b. Target: GluR. Smiles: CCOC(=O)C12CC1\C(=N/O)c1ccccc1O2. References: Litschig S, et al. CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting...

Application:	Low affinity, selective, non-competitive mGluR1b antagonist
CAS	179067-99-3
MW:	247.25 D

From 46.00€ *

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