Corydaline

Description: 1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastric accommodation. 3. Corydaline exhibits the anti-acetylcholinesterase, antiallergic, and antinociceptive activities. 4. Corydaline has potent inhibition of CYP2C19 and CYP2C9. Target: Opioid Receptor, AChE, P450, Virus Protease. Smiles: COc1cc2CCN3Cc4c(ccc(OC)c4OC)C(C)C3c2cc1OC. References: Ji H Y , Lee H , Kim J H , et al. In vitro metabolism of corydaline in human liver microsomes and hepatocytes using liquid chromatography-ion trap mass spectrometry[J]. Journal of Separation Science, 2012, 35(9):1102-1109.