268 products were found matching "K01049"!

Acetylcholinesterase, also known as AChE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. It is mainly found at neuromuscular junctions and cholinergic synapses in the central nervous system, where its activity serves to...

Description: Acetylcholinesterase Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P22303.

Acetylcholinesterase (AChE) is a highly conserved homotetrameric carboxylesterase that is composed of four ~70 kDa subunits, each containing a single active site. In the electric eel (E. electricus), AChE is highly expressed in the electric organs at the posterior innervated membrane, where it hydrolyzes...

Cayman's Acetylcholinesterase Activity Assay Kit provides a convenient method of detecting total cholinesterase (ChE) and/or AChE activity in serum, plasma, tissue homogenates, and cell lysates. This assay enables the specific detection of AChE activity by leveraging Cayman's proprietary BChE inhibitor formulated to...

(-)-Physostigmine is an alkaloid that has been found in Calabar beans and a cholinergic agent. It inhibits acetylcholinesterase (AChE, IC50 = 0.67 nM). (-)-Physostigmine (10 µM) inhibits ChE and increases vagal stimulation-induced ACh output in isolated chicken heart. In vivo, (-)-physostigmine (200 and 400 µg/kg)...

Description: Ipidacrine (NIKâ??247) (NIKâ??247) is an Antidementia Agent. Target: Potassium Channel, Sodium Channel, Cholinesterase (ChE), Others. Smiles: Nc1c2CCCc2nc2CCCCc12. References: Kojima J , Onodera K , Ozeki M , et al. Ipidacrine (NIK7): A Review of Multiple Mechanisms as an Antidementia Agent[J]. CNS...

YM-443, N-[2-[bis(1-methylethyl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxamide, monohydrochloride

Donepezil hydrochloride is a centrally acting reversible acetylcholinesterase inhibitor. Its main therapeutic use is in the treatment of Alzheimer's disease.

Donepezil is an inhibitor of acetylcholinesterase (AChE, IC50 = 6.7 nM). It is selective for AChE over butyrylcholinesterase (BChE, IC50 = 988 nM). Donepezil (0.1 and 1 µM) inhibits the production of nitric oxide (NO) and TNF-alpha induced by oligomeric amyloid-beta (1-42) (AbetaO1-42) in primary rat microglial...

An internal standard for the quantification of edrophonium by GC- or LC-MS

An internal standard for the quantification of acotiamide by GC- or LC-MS. Formulation: A solid. InChI: InChI=1S/C21H30N4O5S.ClH/c1-12(2)25(13(3)4)8-7-22-20(28)15-11-31-21(23-15)24-19(27)14-9-17(29-5)18(30-6)10-16(14)26,/h9-13,26H,7-8H2,1-6H3,(H,22,28)(H,23,24,27),1H/i5D3,6D3,. InChIKey: VQEKQYLTAIVCBW-PKKCSIJHSA-N....

Acetylcholinesterase, also known as AChE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. It is mainly found at neuromuscular junctions and cholinergic synapses in the central nervous system, where its activity serves to...