269 products were found matching "K01049"!

Acetylcholinesterase, also known as AChE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. It is mainly found at neuromuscular junctions and cholinergic synapses in the central nervous system, where its activity serves to...

Description: Acetylcholinesterase Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P22303.

Acetylcholinesterase (AChE) is a highly conserved homotetrameric carboxylesterase that is composed of four ~70 kDa subunits, each containing a single active site. In the electric eel (E. electricus), AChE is highly expressed in the electric organs at the posterior innervated membrane, where it hydrolyzes...

Cayman's Acetylcholinesterase Activity Assay Kit provides a convenient method of detecting total cholinesterase (ChE) and/or AChE activity in serum, plasma, tissue homogenates, and cell lysates. This assay enables the specific detection of AChE activity by leveraging Cayman's proprietary BChE inhibitor formulated to...

Description: Ipidacrine (NIKâ??247) (NIKâ??247) is an Antidementia Agent. Target: Potassium Channel, Sodium Channel, Cholinesterase (ChE), Others. Smiles: Nc1c2CCCc2nc2CCCCc12. References: Kojima J , Onodera K , Ozeki M , et al. Ipidacrine (NIK7): A Review of Multiple Mechanisms as an Antidementia Agent[J]. CNS...

Donepezil hydrochloride is a centrally acting reversible acetylcholinesterase inhibitor. Its main therapeutic use is in the treatment of Alzheimer's disease.

Donepezil is an inhibitor of acetylcholinesterase (AChE, IC50 = 6.7 nM). It is selective for AChE over butyrylcholinesterase (BChE, IC50 = 988 nM). Donepezil (0.1 and 1 µM) inhibits the production of nitric oxide (NO) and TNF-alpha induced by oligomeric amyloid-beta (1-42) (AbetaO1-42) in primary rat microglial...

YM-443, N-[2-[bis(1-methylethyl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxamide, monohydrochloride

Acetylcholinesterase, also known as AChE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. It is mainly found at neuromuscular junctions and cholinergic synapses in the central nervous system, where its activity serves to...

beta-Amyrin is a natural pentacyclic triterpenoid commonly found in plants. It is a member of the oleanane group of secondary metabolites biosynthesized from squalene in the triterpenoid pathway. beta-Amyrin inhibits collagen-induced platelet aggregation (IC50 = 10.5 µM), inhibits acetylcholinesterase (IC50 = 165...

Acetylcholinesterase, also known as AChE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. It is mainly found at neuromuscular junctions and cholinergic synapses in the central nervous system, where its activity serves to...

Rivastigmine is a cholinesterase (ChE) inhibitor that inhibits butyryl ChE (BChE) and acetyl ChE (AChE, IC50s = 0.037 and 4.15 µM, respectively). It increases levels of secreted amyloid precursor protein (sAPP) and decreases levels of soluble amyloid-beta (1-40) and various N-terminal cleavage products in primary...