CMPD101

Item number	Size	Delivery time	Price
TGM-T14989-1mg	1 mg	7 - 10 business days*	60.00€
TGM-T14989-5mg	5 mg	7 - 10 business days*	128.00€
TGM-T14989-1mL	1 ml	7 - 10 business days*	133.00€
TGM-T14989-10mg	10 mg	7 - 10 business days*	206.00€
TGM-T14989-25mg	25 mg	7 - 10 business days*	417.00€
TGM-T14989-50mg	50 mg	7 - 10 business days*	626.00€

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Description: CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and... more

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Product information "CMPD101"

Description: CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM). Which can be used for the study of heart failure. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCalpha with IC50s of 3.1 µM , 2.3 µM, 1.4 µM and 8.1 µM, respectively. Target: PKC, ROCK, GRK. Smiles: Cn1c(CNc2cccc(c2)C(=O)NCc2ccccc2C(F)(F)F)nnc1-c1ccncc1. References: Okawa T, et al. Design, Synthesis, and Evaluation of the Highly Selective and Potent G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitor for the Potential Treatment of Heart Failure. J Med Chem. 2017 Aug 24,60(16):6942-6990.

Supplier:	TargetMol
Supplier-Nr:	T14989

Properties

Application:	GRK2 inhibitor, GRK3 inhibitor
MW:	466.46 D
Formula:	C24H21F3N6O

Database Information

CAS :	865608-11-3\| Matching products
KEGG ID :	K00910 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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