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CL2A-SN38

BPS
CL2A-SN38
Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-82256-1 50 mg - -

3 - 15 business days*

2,253.00€
BPS-82256-2 100 mg - -

3 - 15 business days*

3,862.00€
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
 
Description Product Citations Certificate of Analysis Reviews 0
Description
CL2A-SN38 is a SN38 derivative with a Mal-PEG attached peptide linker, it can easily react with... more
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Product information "CL2A-SN38"
CL2A-SN38 is a SN38 derivative with a Mal-PEG attached peptide linker, it can easily react with antibody to form an antibody-drug conjugate (ADC). SN-38 is a potent DNA Topoisomerase I inhibitor. CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A linker is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond.
Supplier: BPS Bioscience
Supplier-Nr: 82256

Properties

Application: ADC payload, potent DNA Topoisomerase I inhibitor
MW: 1480,6 D
Formula: C73H97N11O22

Database Information

KEGG ID : K03163 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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