cis-ACCP

cis-ACCP
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10012583-1 1 mg -

6 - 10 business days*

28.00€
Cay10012583-5 5 mg -

6 - 10 business days*

124.00€
Cay10012583-10 10 mg -

6 - 10 business days*

220.00€
Cay10012583-50 50 mg -

6 - 10 business days*

963.00€
 
Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in... more
Product information "cis-ACCP"
Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins, thus enabling cell migration. Overexpression of MMPs are linked to diseases such as cancer, arthritis, osteoporosis, and arteriosclerosis. cis-ACCP is a reversible and competitive inhibitor of type IV collagen-specific MMP-2 and MMP-9 with preference towards MMP-2 (IC50 = 4 and 20 µM, respectively). At 100 µM, cis-ACCP prevents 90% of tumor cell invasion across matrigel-coated membranes in vitro. Formal Name: P-[[[(1R,2S)-2-aminocyclohexyl]amino]carbonyl]-phosphonic acid. CAS Number: 777075-44-2. Molecular Formula: C7H15N2O4P. Formula Weight: 222.2. Purity: >95%. Formulation: A crystalline solid. Solubility: Ethanol: 0.15 mg/ml, PBS (pH 7.2): 0.30 mg/ml. SMILES: N[C@H]1CCCC[C@H]1NC(P(O)(O)=O)=O. InChi Code: InChI=1S/C7H15N2O4P/c8-5-3-1-2-4-6(5)9-7(10)14(11,12)13/h5-6H,1-4,8H2,(H,9,10)(H2,11,12,13)/t5-,6+/m0/s1. InChi Key: XHCXISPZIHYKQD-NTSWFWBYSA-N.
Keywords: P-[[[(1R,2S)-2-aminocyclohexyl]amino]carbonyl]-phosphonic acid
Supplier: Cayman Chemical
Supplier-Nr: 10012583

Properties

Application: MMP inhibitor
MW: 222.2 D
Formula: C7H15N2O4P
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 777075-44-2| Find alternatives
KEGG ID : K01398 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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