227 products were found matching "K01398"!

Type IV collagenase, 72-kDa, is officially designated as matrix metalloproteinase-2 (MMP2). It is also known as gelatinase. MMP-2 plays an essential role in angiogenesis and arteriogenesis, two processes critical to restoration of tissue perfusion after ischemia. MMP-2 expression is increased in tissue ischemia, but...

Type IV collagenase, 72-kD, is officially designated matrix metalloproteinase-2 (MMP2). It is also known as gelatinase, 72-kD. MMP-2 plays an essential role in angiogenesis and arteriogenesis, two processes critical to restoration of tissue perfusion after ischemia. MMP-2 expression is increased in tissue ischemia,...

Type IV collagenase, 72-kD, is officially designated matrix metalloproteinase-2 (MMP2). It is also known as gelatinase, 72-kD. MMP-2 plays an essential role in angiogenesis and arteriogenesis, two processes critical to restoration of tissue perfusion after ischemia. MMP-2 expression is increased in tissue ischemia,...

ARP 101 is an inhibitor of matrix metalloproteinase-2 (MMP-2, IC50 = 0.09 nM). It is selective for MMP-2 over MMP-1, -3, -7, -8, -9, and -14 (IC50s = 147, 50, >1,000, 1.6, 6.7, and 9.8 nM, respectively). ARP 101 inhibits the migration and invasion of human umbilical vein endothelial cells (HUVECs) and induces...

Product Description: MMP2 is an enzyme that plays a crucial role in extracellular matrix remodeling and tissue repair. It functions by cleaving type IV collagen, a major component of basement membranes, and is involved in various physiological processes such as menstruation, angiogenesis, and bone remodeling. MMP2...

Product Description: MMP2 is an enzyme that plays a crucial role in extracellular matrix remodeling and tissue repair. It functions by cleaving type IV collagen, a major component of basement membranes, and is involved in various physiological processes such as menstruation, angiogenesis, and bone remodeling. MMP2...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat MMP2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat MMP2. Next,...

The matrix metalloproteinases (MMPs) are a family of proteases that target many extracellular proteins including other proteases, growth factors, cell surface receptors, and adhesion molecules. Protein Function: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the...

MMP inhibitor III is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs, IC50s = 4.1, 3.6, 8.2, and 6.4 nM for MMP-1, MMP-2, MMP-12, and MMP-13, respectively). It also inhibits MMP-3 with an IC50 value of 134 nM. MMP inhibitor III reduces ionomycin-induced shedding of CD146 in human microvascular lung...

Protein function: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins...

GM 6001 is a potent, reversible broad spectrum inhibitor of zinc-containing proteases, including matrix metalloproteinases (MMPs). It inhibits zinc-containing thermolysin and elastase from P. aeruginosa, both with Ki values of 20 nM. GM 6001 inhibits MMP-1, -2, -7, -8, -9, -12, -13, -14, -16, and -26 with Ki or IC50...

Batimastat is a broad spectrum inhibitor of matrix metalloproteinases (MMP), with IC50 values of 1-5 nM for all MMPs tested, including MMP-1, -2, -3, -7, -9, -13, and -14. It also potently inhibits TNFalpha-converting enzyme (IC50 = 14.9 nM). Because of its action on MMPs, batimastat has anti-proliferative,...