CCT245737

Item number	Size	Delivery time	Price
TGM-T7080-1mg	1 mg	7 - 10 business days*	32.00€
TGM-T7080-2mg	2 mg	7 - 10 business days*	45.00€
TGM-T7080-5mg	5 mg	7 - 10 business days*	72.00€
TGM-T7080-1mL	1 ml	7 - 10 business days*	79.00€
TGM-T7080-10mg	10 mg	7 - 10 business days*	114.00€
TGM-T7080-25mg	25 mg	7 - 10 business days*	223.00€
TGM-T7080-50mg	50 mg	7 - 10 business days*	367.00€
TGM-T7080-100mg	100 mg	7 - 10 business days*	550.00€

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Description: CCT245737 (SRA737) is an orally active and selective Chk1 inhibitor (IC50: 1.3 nM),... more

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Product information "CCT245737"

Description: CCT245737 (SRA737) is an orally active and selective Chk1 inhibitor (IC50: 1.3 nM), CCT245737 shows much less activity against Chk2 (IC50: 2440 nM). Target: Chk. Smiles: FC(F)(F)c1cnc(Nc2cnc(cn2)C#N)cc1NC[C@H]1CNCCO1. References: Osborne JD, et al. Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737). J Med Chem. 2016 Jun 9,59(11):5221-37.

Keywords:	SRA737
Supplier:	TargetMol
Supplier-Nr:	T7080

Properties

Application:	Potent Chk1 inhibitor
MW:	379.34 D
Formula:	C16H16F3N7O

Database Information

CAS :	1489389-18-5\| Matching products
KEGG ID :	K02216 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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