CAY10756

CAY10756 is a brain-penetrant inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50 = 21 nM). It inhibits autophosphorylation of ASK1 in HEK293T cells (IC50 = 138 nM).Formal Name: 3-methoxy-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]-1-(2-pyrazinyl)-1H-pyrazole-4-carboxamide. CAS Number: 2411382-24-4. Molecular Formula: C19H19N9O2. Formula Weight: 405.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: Chloroform: 10 mg/ml. lambdamax: 275, 318 nm. SMILES: O=C(C1=CN(C2=NC=CN=C2)N=C1OC)NC3=CC=CC(C4=NN=CN4C(C)C)=N3. InChi Code: InChI=1S/C19H19N9O2/c1-12(2)27-11-22-25-17(27)14-5-4-6-15(23-14)24-18(29)13-10-28(26-19(13)30-3)16-9-20-7-8-21-16/h4-12H,1-3H3,(H,23,24,29). InChi Key: FTPVMITWJIXRGQ-UHFFFAOYSA-N.