Cabozantinib S-malate
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Cabozantinib S-malate (XL184) is the s-malate salt form of cabozantinib, an orally... more
Product information "Cabozantinib S-malate"
Description: Cabozantinib S-malate (XL184) is the s-malate salt form of cabozantinib, an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Target: Apoptosis, c-Met/HGFR, VEGFR, TAM Receptor, c-Kit. Smiles: O[C@@H](CC(O)=O)C(O)=O.COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC. References: You WK, et al. Cancer Res, 2011, 71(14), 4758-4768.
| Keywords: | XL184, Cabozantinib Malate, Cabozantinib |
| Supplier: | TargetMol |
| Supplier-Nr: | T1797 |
Properties
| Application: | Targets kinase insert domain protein receptor [EC:2.7.10.1] (KDR, VEGFR2, CD309) |
| MW: | 635.59 D |
| Formula: | C32H30FN3O10 |
Database Information
| CAS : | 1140909-48-3| Matching products |
| KEGG ID : | K05098 | Matching products |
| Protein Atlas Nr. : | Tyrosine Phosphorylation |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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