Buparlisib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Buparlisib (BKM120) is an orally bioavailable specific oral inhibitor of the... more
Product information "Buparlisib"
Description: Buparlisib (BKM120) is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: 52/166/116/nM for p110alpha, p110beta, and p110delta). Target: Apoptosis, PI3K. Smiles: Nc1cc(c(cn1)-c1cc(nc(n1)N1CCOCC1)N1CCOCC1)C(F)(F)F. References: Burger MT, et al. Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer. ACS Med Chem Lett. 2011 Aug 26,2(10):774-9.
| Keywords: | BKM120, NVP-BKM120 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1827 |
Properties
| Application: | Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta |
| MW: | 410.39 D |
| Formula: | C18H21F3N6O2 |
Database Information
| CAS : | 944396-07-0| Matching products |
| KEGG ID : | K00922 | Matching products |
| Protein Atlas Nr. : | Lipid / Phosphoinositial Signaling |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H341, H372 |
| P Phrases: | P201, P202, P260, P264, P270, P280, P314, P321, P330, P301+P310, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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