BMS-986176

Item number	Size	Delivery time	Price
TGM-T35856-1mg	1 mg	7 - 10 business days*	165.00€
TGM-T35856-5mg	5 mg	7 - 10 business days*	351.00€
TGM-T35856-1mL	1 ml	7 - 10 business days*	375.00€
TGM-T35856-10mg	10 mg	7 - 10 business days*	525.00€
TGM-T35856-25mg	25 mg	7 - 10 business days*	848.00€
TGM-T35856-50mg	50 mg	7 - 10 business days*	1,156.00€
TGM-T35856-100mg	100 mg	7 - 10 business days*	1,564.00€
TGM-T35856-500mg	500 mg	7 - 10 business days*	6,014.00€

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Description: AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1... more

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Product information "BMS-986176"

Description: AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM). Target: AAK1 (AP2 associated kinase 1). Smiles: CC(C)C[C@](C)(N)COc1ccc(nc1C(F)F)-c1ccnc(c1)C(F)F. References: Guanglin Luo, et al. Discovery of ( S)-1-((2',6-Bis(difluoromethyl)-[2,4'-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine (BMS-986176/LX-9211): A Highly Selective, CNS Penetrable, and Orally Active Adaptor Protein-2 Associated Kinase 1 Inhibitor in Clinical Trials for the Treatment of Neuropathic Pain. J Med Chem. 2022 Mar 24,65(6):4457-4480.

Supplier:	TargetMol
Supplier-Nr:	T35856

Properties

MW:	385.4 D
Formula:	C19H23F4N3O

Database Information

CAS :

1815613-42-3| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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