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Item number: Cay43668-1

An AAK1 inhibitor (IC50 = 2 nM), increases the latency to paw withdrawal in a rat model of streptozotocin-induced diabetic neuropathic pain at 0.3 or 3 mg/kg

Keywords:	LX9211, (2S)-1-[[2',6-bis(difluoromethyl)[2,4'-bipyridin]-5-yl]oxy]-2,4-dimethyl-2-pentanamine
Application:	AAK1 (AP2-associated kinase) inhibitor
CAS	1815613-42-3
MW:	385.41 D

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BMS-986176

Item number: TGM-T35856-100mg

Description: AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM). Target: AAK1 (AP2 associated kinase 1). Smiles: CC(C)C[C@](C)(N)COc1ccc(nc1C(F)F)-c1ccnc(c1)C(F)F. References: Guanglin Luo, et al. Discovery of (...

CAS	1815613-42-3
MW:	385.4 D

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