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Description: BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specifically disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM). Target: E1/E2/E3 Enzyme. Smiles: COc1ccccc1CNC(=O)C(C)NC(=O)C1CCN(CC1)S(=O)(=O)c1ccccc1. References: Coon T A , Mckelvey A C , Lear T , et al. The proinflammatory role of HECTD2 in innate immunity and experimental lung injury[J]. ence Translational Medicine, 2015, 7(295):295ra109.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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