Azide-PEG8-Val-Cit-PAB-MMAE

Azide-PEG8-Val-Cit-PAB-MMAE
Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-82277-1 1 mg - -

3 - 15 business days*

975.00€
BPS-82277-2 5 mg - -

3 - 15 business days*

2,213.00€
BPS-82277-3 10 mg - -

3 - 15 business days*

3,121.00€
 
Azide-PEG8-Val-Cit-PAB-MMAE is a cleavable ADC linker which contains an azide, a PEG spacer, a... more
Product information "Azide-PEG8-Val-Cit-PAB-MMAE"
Azide-PEG8-Val-Cit-PAB-MMAE is a cleavable ADC linker which contains an azide, a PEG spacer, a Val-Cit dipeptide, a PAB group, and an MMAE warhead. The azide is free to participate in click chemistry with terminal alkynes or strained cyclooctynes such as DBCO or BCN. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient MMAE payload delivery via an elimination mechanism within the PAB structure.
Supplier: BPS Bioscience
Supplier-Nr: 82277

Properties

Application: ADC payload, click chemistry, cleavable alkyne-reactive ADC linker, apoptosis inducer
MW: 1573,0 D
Formula: C77H129N13O21

Database Information

KEGG ID : K07375 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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