AZD 5153 (6-hydroxy-2-naphthoic acid)

Item number	Size	Manual	SDS	Delivery time	Price
Cay42341-5	5 mg	-	-	6 - 10 business days*	201.00€
Cay42341-10	10 mg	-	-	6 - 10 business days*	321.00€
Cay42341-50	50 mg	-	-	6 - 10 business days*	1,001.00€
Cay42341-100	100 mg	-	-	6 - 10 business days*	1,401.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

A bivalent BRD4 inhibitor (IC50 = 5 nM) that simultaneously binds two bromodomains in BRD4,... more

Close menu

Product information "AZD 5153 (6-hydroxy-2-naphthoic acid)"

A bivalent BRD4 inhibitor (IC50 = 5 nM) that simultaneously binds two bromodomains in BRD4, demonstrates antitumor activity in multiple xenograft models of acute myeloid leukemia, multiple myeloma, and diffuse large B cell lymphoma. Formulation: A solid. InChI: InChI=1S/C25H33N7O3.C11H8O3/c1-18-24(33)29(2)14-15-30(18)16-17-35-21-6-4-19(5-7-21)20-10-12-31(13-11-20)23-9-8-22-26-27-25(34-3)32(22)28-23,12-10-4-3-7-5-9(11(13)14)2-1-8(7)6-10/h4-9,18,20H,10-17H2,1-3H3,1-6,12H,(H,13,14)/t18-,/m1./s1. InChIKey: UNZQBHXKCHECEC-GMUIIQOCSA-N. SMILES: COC1=NN=C2N1N=C(N3CCC(C4=CC=C(OCCN5[C@H](C)C(N(C)CC5)=O)C=C4)CC3)C=C2.OC6=CC(C=CC(C(O)=O)=C7)=C7C=C6

Keywords:	AZD 5153 HNT salt, 6-hydroxy-2-naphthalenecarboxylic acid, compd. with (3R)-4-[2-[4-[1-(3-methoxy-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-4-piperidinyl]phenoxy]ethyl]-1,3-dimethyl-2-piperazinone (1:1)
Supplier:	Cayman Chemical
Supplier-Nr:	42341

Properties

Application:	Bivalent BRD4 inhibitor
Immunogen:	667.8
MW:	667.8 D
Formula:	C25H33N7O3 . C11H8O3
Purity:	>95%
Format:	Solid

Database Information

CAS :	1869912-40-2\| Matching products
KEGG ID :	K11722 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: -20°C)
Signal Word:	Danger
GHS Hazard Pictograms:
H Phrases:	H302, H372, H410
P Phrases:	P260, P264, P270, P273, P301+310, P314, P330, P391, P501